Download Acute Brain and Spinal Cord Injury: Evolving Paradigms and by Anish Bhardwaj, Jeffrey R. Kirsch PDF

By Anish Bhardwaj, Jeffrey R. Kirsch

The scientific administration of sufferers with acute mind and spinal twine damage has developed considerably with the appearance of recent diagnostic and healing modalities. Editors Bhardwaj, Ellegala, and Kirsch current Acute mind and Spinal twine Injury , a brand new stand-alone connection with aid today’s neurologists and neurosurgeons preserve abreast of all of the contemporary developments in mind and spinal wire damage. Divided into 5 sections, stressful mind damage, ischemic stroke, intracerebral and subarachnoid hemorrhage, and spinal twine damage, this article bargains the most up-tp-date scientific technology and highlights controversies within the medical administration of sufferers with acute mind and spinal twine injuries.

Acute mind and Spinal wire Injury :

  • each part delineates diagnostic and tracking instruments, pharmacotherapies, and interventional and surgical remedies are covered
  • examines and explores lately released laboratory trials and research
  • incorporates over 50 diagrams and figures for concise verbal exchange of clinical information

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Extra info for Acute Brain and Spinal Cord Injury: Evolving Paradigms and Management

Example text

Interestingly, rebound ICP to levels of greater than 35 mmHg was associated with 100% mortality (24). An observational study reported on clinical and physiologic parameters of DC in 26 patients treated as part of a standardized protocol (25). Bifrontal DC was associated with significant 50% reduction in mean ICP from 37 to 18 mmHg, also reducing ICP wave amplitude. While almost 70% of patients were deemed to have had a favorable outcome, it is difficult to assess the effect of ICP reduction by DC on this parameter (25).

INITIAL NEUROLOGIC ASSESSMENT Glasgow Coma Scale Score The examination begins with a careful assessment for external head trauma. The neurologic examination is characterized by the Glasgow Coma Scale (GCS) score (Table 1). Developed in 1974 by Jennett and Teasdale, the GCS is the most widely used method of determining the severity of TBI. Included in the assessment are eye opening, verbal response, and motor response, which provide a general gauge of the level of consciousness (8). A well-documented prehospital GCS score is helpful, but situations that arise outside a health care setting can complicate the GCS calculation.

Furthermore, patients determined by CT imaging to have (by TCDB classification) diffuse injury I–II have better outcomes at 12 months than those with diffuse injury IV or focal injury (18). Secondary Brain Injury While primary brain injury refers to a particular traumatic insult, secondary brain injury refers to cellular processes that unfold hours to days after the initial brain injury, ultimately compounding the effects of the initial injury. Secondary brain injury results not only from the delayed effects of primary brain injury, but also from aggravating factors such as hypotension, hypoxia, inadequate cerebral perfusion pressure (CPP), and intracranial hypertension (19).

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