By Girish Fatterpekar, Thomas P. Naidich, Peter M. Som
Useful and clinically concentrated, mind and backbone Imaging - a identify within the instructing documents sequence - provide you with over three hundred fascinating and well-presented instances that can assist you greater diagnose any affliction of the mind and backbone. specialist within the box, Dr. Girish Fatterpekar, MD makes use of a logical association all through, making referencing tricky diagnoses more straightforward than ever ahead of. targeted discussions of modern day modalities and applied sciences continue you modern, and not easy diagnostic questions probe your wisdom of the fabric. This distinct, case-based source provide you with a great way to sharpen your diagnostic talents and learn for board assessments.
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Extra info for Brain and Spine
1) demonstrates vermian hypoplasia. Axial T2WI (Fig. 2) demonstrates a vermian cleft with apposition of the cerebellar hemispheres. Coronal MPRAGE (Fig. 3) demonstrates “triangular-shaped” fourth ventricle. Axial MPRAGE (Fig. ” Diagnosis: Joubert syndrome. DISCUSSION Definition/Background Joubert syndrome (JS) is an autosomal-recessive disorder characterized by a specific mid-hindbrain malformation, presenting with hypotonia, cerebellar ataxia, and developmental delay/mental retardation. Mutations in the NPHP1, AHI1, and CEP290 genes have been described in some patients with JS.
Sagittal T1WI demonstrates a prominent retrocerebellar cystic-appearing lesion (star). There is no elevation of the torcula herophili. The posterior fossa is normal in size. There is no evidence for hydrocephalus. Figure 2. Axial T2WI demonstrates normal-appearing fourth ventricle, vermis, and cerebellar hemispheres. Figure 3. Axial DWI does not demonstrate any restricted diffusion. Diagnosis: Mega cisterna magna. Case 18 DEMOGRAPHICS/CLINICAL HISTORY The patient is a neonate with persistent hypoglycemia.
Strand RD, Barnes PD, Poussaint TY, et al: Cystic retrocerebellar malformations: Unification of the Dandy-Walker complex and the Blake’s pouch cyst, Pediatr Radiol 23:258–260, 1993. Case 17 35 Figure 1. Sagittal T1WI demonstrates a prominent retrocerebellar cystic-appearing lesion (star). There is no elevation of the torcula herophili. The posterior fossa is normal in size. There is no evidence for hydrocephalus. Figure 2. Axial T2WI demonstrates normal-appearing fourth ventricle, vermis, and cerebellar hemispheres.