Download Management of Chronic Viral Hepatitis by Graham Foster PDF

By Graham Foster

St. Mary's sanatorium, London, united kingdom. Pocket-sized illustrated textual content for these drawn to the administration of viral hepatitis. transparent diagnostic algorithms are supplied besides multiple-choice questions at bankruptcy finish. Softcover.

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Sample text

Disease progression is similar for all of them) but the response to therapy is influenced by genotype, and different durations of treatment are required to treat the different genotypes (see page 56). g. genotype 1 has been subdivided into type 1a and type 1b) but this is not of value in clinical practice. Replication of the hepatitis C virus Our knowledge of the replication of the hepatitis C virus is still incomplete. The information that is currently available is being used to develop new antiviral agents and it is likely that the currently identified drug targets will lead to novel therapeutic agents in the foreseeable future.

Genotype 4 is common in western Europe D. Genotype is commonly determined by examining the sequence of the 5Ј non-coding region E. The viral genotype can be used to predict the likelihood of cirrhosis 2. In chronic hepatitis C virus infection: A. Spontaneous clearance is common B. In general 30% of patients will develop cirrhosis after 30 years C. Alcohol consumption reduces the incidence of vascular disease and is likely to be beneficial 44 Management of Chronic Viral Hepatitis D. Patients with normal liver function tests do not need to undergo liver biopsy since mild disease is always found E.

The liver biopsy allows an accurate assessment of liver injury and permits confirmation that the liver disease is due entirely to hepatitis C. In general, patients with mild liver damage should not be treated, and therapy should be reserved for those with moderate to severe disease. The precise definition of moderate to To ensure equity of access to therapy for hepatitis C and to ensure that all patients are treated appropriately, most liver centres have established severity criteria that must be met before a patient is eligible for treatment.

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