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By Mark K. Ferguson, M. Brian Fennerty

Finished and up to date research of GERD Has specialize in treatments to failed therapy of the illness

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65. Barrett NR. Hiatus hernia. Br Med J 1960;2:247–252. 66. Nissen R. Eine einfache Operation zur Beeinflussung der Refluxoesophagitis. Schweiz Med Wochenschr 1956;86:590–592. 67. Nissen R. Gastropexy and “fundoplication” in surgical treatment of hiatal hernia. Am J Dig Dis 1961;6: 954–961. 68. Skinner DB, Belsey RHR. Surgical management of esophageal reflux and hiatus hernia. Long-term results with 1,030 patients. J Thorac Cardiovasc Surg 1967;53: 33–54. 69. Hill LD. An effective operation for hiatal hernia: an eight-year appraisal.

Magnesium containing antacids may cause diarrhea and should be avoided in patients with heart failure, renal 33 MEDICAL MANAGEMENT OF GERD: ALGORITHMS AND OUTCOMES insufficiency, and late trimester pregnancy. Aluminum-containing antacids may cause constipation and should also be avoided in patients with chronic renal insufficiency. Overall, antacids have a marginal benefit as a therapy for GERD. They have no role as primary therapy in a patient with known erosive esophagitis. Antacids may offer some benefit to the patient with rare and episodic heartburn in which case they do have the benefit of providing rapid but unfortunately temporary symptom relief.

Gastroenterology 1975;68:1114–1118. 104. McCallum RW, Fink SM, Winnan J, Avella J, Callachan C. Metoclopramide in gastroesophageal reflux disease: rationale for use and results of a double-blind trial. Am J Gastroenterol 1984;79:165–172. 105. Farrell RK, Roling GT, Castell DO. Stimulation of the incompetent lower esophageal sphincter: a possible advance in therapy of heartburn. Am J Dig Dis 1973;18: 646–650. 106. Farrell RL, Roling GT, Castell DO. Cholinergic therapy of chronic heartburn. Ann Intern Med 1974;80: 573–576.

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