Download Pancreatic beta cell. Volume 95, Vitamins and hormones by Gerald Litwack PDF

By Gerald Litwack

First released in 1943, Vitamins and Hormones is the longest-running serial released by way of educational Press.

The sequence offers up to date details on nutrition and hormone study spanning facts from molecular biology to the hospital. A quantity can specialise in a unmarried molecule or on a sickness that's regarding supplements or hormones.  A hormone is interpreted largely in order that comparable ingredients, corresponding to transmitters, cytokines, development components and others may be reviewed.

This quantity makes a speciality of the pancreatic beta cell.

Key features:

  • Expertise of the contributors
  • Coverage of an enormous array of subjects
  • In intensity present info on the molecular to the scientific levels
  • Three-dimensional buildings in color
  • Elaborate signaling pathways

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Additional info for Pancreatic beta cell. Volume 95, Vitamins and hormones

Example text

The Journal of Biological Chemistry, 286(21), 18383–18396. , Wollheim, C. , & Satrustegui, J. (2009). Requirement for aralar and its Ca2 þ -binding sites in Ca2 þ signal transduction in mitochondria from INS-1 clonal beta-cells. The Journal of Biological Chemistry, 284(1), 515–524. McClenaghan, N. , Barnett, C. , & Flatt, P. R. (1998). Na þ cotransport by metabolizable and nonmetabolizable amino acids stimulates a glucose-regulated insulinsecretory response. Biochemical and Biophysical Research Communications, 249(2), 299–303.

At least three steps are involved in protein translocation from the cytosol to the ER: (1) recognition and targeting of nascent polypeptides to the ER membrane; (2) translocation of proteins across the ER membrane; and (3) signal peptide cleavage, protein folding, and maturation in the ER. Here, rather than more extensive reviews of protein targeting and translocation across the ER membrane (Cross, Sinning, Luirink, & High, 2009; Driessen & Nouwen, 2008; Rapoport, 2007), we focus on key events likely to be important for preproinsulin, highlighting recent advances in understanding how defects in these events may cause pancreatic beta cell failure and diabetes.

Clinical Science (London, England), 117(9), 321–330. Berne, C. (1975). The metabolism of lipids in mouse pancreatic islets. The biosynthesis of triacylglycerols and phospholipids. The Biochemical Journal, 152(3), 667–673. , Malthouse, J. , McClenaghan, N. , Flatt, P. , et al. (2003). 13C NMR analysis reveals a link between L-glutamine metabolism, D-glucose metabolism and gamma-glutamyl cycle activity in a clonal pancreatic beta-cell line. Diabetologia, 46(11), 1512–1521. , Malthouse, J. , Brindle, K.

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