By Demosthenes Bouros
Up-to-date to mirror the newest medical advances and applied sciences within the analysis and remedy of pleural ailments, this new moment variation explores the constitution and serve as of those illnesses and malignancies, from tuberculosis and asbestos to pleurisy and pneumothorax. Edited by way of best overseas professionals in pulmonary medication, this finished advisor is a useful source for pulmonologists, radiologists, and demanding care physicians. Pleural sickness, moment variation highlights: molecular and diagnostic ways interventional functions, together with pleural thoracentesis and closed biopsy, chest tube insertion, pleural lavage, scientific thoracoscopy, and VATS biomarkers and proteomics translational medication techniques, new therapy methodologies, and scientific manifestations numerous diagnostic assessments and the significance of scientific review within the differential prognosis of a pleural effusion new surgical and non-surgical ideas to spot and diagnose pleural illnesses, together with: clinical thoracoscopy, pleural lavage, intrapleural fibrinolytics, image-guided small bore catheters, video-assisted thoracoscopic surgical procedure (VATS), pleuroperitoneal shunt, and extrapleural pneumonectomy
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Additional resources for Pleural Disease, Second Edition (Lung Biology in Health and Disease)
Prostaglandins Leukot Essent Fatty Acids 1994; 51:329–335. Rennard S, Jaurand M, Bignon J, et al. Connective tissue matrix of the pleura. In: Chretien J, Bignon J, Hirsch A, eds. The Pleura in Health and Disease, Vol. 5. New York, NY: Marcel Dekker, 1985:69–85. Antony VB. Pathogenesis of malignant pleural effusions and talc pleurodesis. Pneumologie 1999; 53:493–498. Ponta H. The CD44 protein family. Int J Biochem Cell Biol 1998; 30:299–305. Bourguignon LY, Lokeshwar VB, Chen X, et al. Hyaluronic acid-induced lymphocyte signal transduction and HA receptor (GP85/CD44)-cytoskeleton interaction.
Activated–T lymphocytes orchestrate specific immune responses in the pleural space. Mesothelial cells contribute to the cytokines that allow for an undifferentiated T cell to become a T-helper (Th)1- or Th2-type cell that leads to different responses in the pleural space (7). Thus, the defense mechanisms of the pleura include functions starting from providing a mechanical barrier to invasion as well as a sophisticated, multilayered, and coordinated system of cytokines and recruited cells. II. Cytokine Networks in the Pleural Space Cytokines are polypeptide structures with multiple biological functions and are key ingredients for the process of initiation, perpetuation, and resolution of the inflammatory response of the pleura.
KATERINA MALAGARI Medical School of University of Athens, Athens, and Department of Radiology, Attikon University Hospital, Haidari, Athens, Greece I. Introduction A variety of imaging techniques can be used to evaluate the pleura and the pleural space. Standard radiographs are the most common. Sonography, computed tomography, and magnetic resonance imaging (MRI) have assumed an increasing and important role in the diagnosis of pleural disease. This chapter will discuss a variety of diffuse and focal pleural processes and the contribution of each of these imaging techniques to diagnosis and management of pleural disease.